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Publication

Quorum sensing in the probiotic bacterium Escherichia coli Nissle 1917 (Mutaflor) - evidence that furanosyl borate diester (AI-2) is influencing the cytokine expression in the DSS colitis mouse model.

Christoph A Jacobi | Stefanie Grundler | Chih-Jen Hsieh | Julia Stefanie Frick | Patrick Adam | Georg Lamprecht | Ingo B Autenrieth | Michael Gregor | Peter Malfertheiner
Gut pathogens | 2012

"Quorum sensing" (QS) is the phenomenon which allows single bacterial cells to measure the concentration of bacterial signal molecules. Two principle different QS systems are known, the Autoinducer 1 system (AI-1) for the intraspecies communication using different Acyl-homoserine lactones (AHL) and AI-2 for the interspecies communication. Aim of this study was to investigate QS of Escherichia coli Nissle 1917 (Mutaflor).

Pubmed ID: 22862922

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