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Hierarchical clustering of gene expression patterns in the Eomes + lineage of excitatory neurons during early neocortical development.

David A Cameron | Frank A Middleton | Anjen Chenn | Eric C Olson
BMC neuroscience | 2012

Cortical neurons display dynamic patterns of gene expression during the coincident processes of differentiation and migration through the developing cerebrum. To identify genes selectively expressed by the Eomes + (Tbr2) lineage of excitatory cortical neurons, GFP-expressing cells from Tg(Eomes::eGFP) Gsat embryos were isolated to > 99% purity and profiled.

Pubmed ID: 22852769

Research resources used in this publication

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Associated grants

  • Agency: NINDS NIH HHS, United States
    Id: R01 NS066071
  • Agency: NINDS NIH HHS, United States
    Id: NS066071

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This is a list of tools and resources that we have found mentioned in this publication.


GenePaint (tool)

RRID:SCR_003015

Digital atlas of gene expression patterns in developing and adult mouse. Several reference atlases are also available through this site. Expression patterns are determined by non-radioactive in situ hybridization on serial tissue sections. Sections are available from several developmental ages: E10.5, E14.5 (whole embryos), E15.5, P7 and P56 (brains only). To retrieve expression patterns, search by gene name, site of expression, GenBank accession number or sequence homology. For viewing expression patterns, GenePaint.org features virtual microscope tool that enables zooming into images down to cellular resolution.

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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