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450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy.

Bonnie R Joubert | Siri E Håberg | Roy M Nilsen | Xuting Wang | Stein E Vollset | Susan K Murphy | Zhiqing Huang | Cathrine Hoyo | Øivind Midttun | Lea A Cupul-Uicab | Per M Ueland | Michael C Wu | Wenche Nystad | Douglas A Bell | Shyamal D Peddada | Stephanie J London
Environmental health perspectives | 2012

Epigenetic modifications, such as DNA methylation, due to in utero exposures may play a critical role in early programming for childhood and adult illness. Maternal smoking is a major risk factor for multiple adverse health outcomes in children, but the underlying mechanisms are unclear.

Pubmed ID: 22851337

Research resources used in this publication

None found

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Associated grants

  • Agency: NIEHS NIH HHS, United States
    Id: N0-ES-75558
  • Agency: NIEHS NIH HHS, United States
    Id: P30ES011961
  • Agency: NIEHS NIH HHS, United States
    Id: R01 ES016772
  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK085173
  • Agency: NIEHS NIH HHS, United States
    Id: R01ES016772
  • Agency: NINDS NIH HHS, United States
    Id: 1 UO1 NS 047537-01
  • Agency: Intramural NIH HHS, United States
    Id: Z01 ES049019
  • Agency: NINDS NIH HHS, United States
    Id: U01 NS047537
  • Agency: NIEHS NIH HHS, United States
    Id: P30 ES011961
  • Agency: NIEHS NIH HHS, United States
    Id: R21ES01497
  • Agency: NIEHS NIH HHS, United States
    Id: Z01-ES-49019
  • Agency: NIDDK NIH HHS, United States
    Id: R01DK085173
  • Agency: NIEHS NIH HHS, United States
    Id: N01ES75558

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UCSC Genome Browser (tool)

RRID:SCR_005780

Portal to interactively visualize genomic data. Provides reference sequences and working draft assemblies for collection of genomes and access to ENCODE and Neanderthal projects. Includes collection of vertebrate and model organism assemblies and annotations, along with suite of tools for viewing, analyzing and downloading data.

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