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Publication

Epstein-Barr virus immortalization of human B-cells leads to stabilization of hypoxia-induced factor 1 alpha, congruent with the Warburg effect.

Suhas Darekar | Konstantinos Georgiou | Mariya Yurchenko | Surya Pavan Yenamandra | Georgia Chachami | George Simos | George Klein | Elena Kashuba
PloS one | 2012

Epstein-Barr virus (EBV) encodes six nuclear transformation-associated proteins that induce extensive changes in cellular gene expression and signaling and induce B-cell transformation. The role of HIF1A in EBV-induced B-cell immortalization has not been previously studied.

Pubmed ID: 22848707

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MCF-7 (tool)

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Cell line MCF-7 is a Cancer cell line with a species of origin Homo sapiens (Human)

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