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Micro-RNA-195 and -451 regulate the LKB1/AMPK signaling axis by targeting MO25.

Hao Chen | Gustavo M Untiveros | Laurel A K McKee | Jessica Perez | Jing Li | Parker B Antin | John P Konhilas
PloS one | 2012

Recently, MicroRNAs (miR) and AMP-kinase (AMPK) have emerged as prominent players in the development of cardiac hypertrophy and heart failure. We hypothesized that components of the adenosine monophosphate-activated kinase (AMPK) pathway are targeted by miRs and alter AMPK signaling during pathological cardiac stress.

Pubmed ID: 22844503

Research resources used in this publication

None found

Additional research tools detected in this publication

Antibodies used in this publication

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Associated grants

  • Agency: NHLBI NIH HHS, United States
    Id: HL007249
  • Agency: NICHD NIH HHS, United States
    Id: HD064559
  • Agency: NHLBI NIH HHS, United States
    Id: T32 HL007249
  • Agency: NHLBI NIH HHS, United States
    Id: HL 098256
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL098256
  • Agency: NICHD NIH HHS, United States
    Id: P41 HD064559
  • Agency: NHLBI NIH HHS, United States
    Id: K02 HL105799
  • Agency: NIAMS NIH HHS, United States
    Id: K01 AR052840

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This is a list of tools and resources that we have found mentioned in this publication.


miRBase (tool)

RRID:SCR_003152

Central online repository for microRNA nomenclature, sequence data, annotation and target prediction.Collection of published miRNA sequences and annotation.

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C2C12 (tool)

RRID:CVCL_0188

Cell line C2C12 is a Spontaneously immortalized cell line with a species of origin Mus musculus (Mouse)

View all literature mentions

C2C12 (tool)

RRID:CVCL_0188

Cell line C2C12 is a Spontaneously immortalized cell line with a species of origin Mus musculus (Mouse)

View all literature mentions