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Hippocampal CA1 transcriptional profile of sleep deprivation: relation to aging and stress.

Nada M Porter | Julia H Bohannon | Meredith Curran-Rauhut | Heather M Buechel | Amy L S Dowling | Lawrence D Brewer | Jelena Popovic | Veronique Thibault | Susan D Kraner | Kuey Chu Chen | Eric M Blalock
PloS one | 2012

Many aging changes seem similar to those elicited by sleep-deprivation and psychosocial stress. Further, sleep architecture changes with age suggest an age-related loss of sleep. Here, we hypothesized that sleep deprivation in young subjects would elicit both stress and aging-like transcriptional responses.

Pubmed ID: 22792227

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Associated grants

  • Agency: NIA NIH HHS, United States
    Id: P01 AG010836
  • Agency: NIA NIH HHS, United States
    Id: R01 AG037868
  • Agency: NIA NIH HHS, United States
    Id: AG10836
  • Agency: NIA NIH HHS, United States
    Id: AG037868

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