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Expression of AEG-1 mRNA and protein in colorectal cancer patients and colon cancer cell lines.

Sebastian Gnosa | Yang-Mei Shen | Chao-Jie Wang | Hong Zhang | Johannes Stratmann | Gunnar Arbman | Xiao-Feng Sun
Journal of translational medicine | 2012

Astrocyte elevated gene 1 (AEG-1), an important oncogene, has been shown to be overexpressed in several types of cancers. In colorectal cancer (CRC), the protein level of AEG-1 is up-regulated in tumour tissue compared to normal mucosa, showing prognostic significance. Since little is known about the transcriptional level of AEG-1 expression and its biological pathway in CRC the aim of the present study was to examine the relationship of AEG-1 mRNA expression, the protein level and clinicopathological variables as well as its biology pathway in CRC.

Pubmed ID: 22643064

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SW620 (tool)

RRID:CVCL_0547

Cell line SW620 is a Cancer cell line with a species of origin Homo sapiens (Human)

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SW480 (tool)

RRID:CVCL_0546

Cell line SW480 is a Cancer cell line with a species of origin Homo sapiens (Human)

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