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Injection of human bone marrow and mononuclear cell extract into infarcted mouse hearts results in functional improvement.

Franca S Angeli | Yan Zhang | Richard Sievers | Kristine Jun | Sarah Yim | Andrew Boyle | Yerem Yeghiazarians
The open cardiovascular medicine journal | 2012

We have previously shown that mouse whole bone marrow cell (BMC) extract results in improvement of cardiac function and decreases scar size in a mouse model of myocardial infarction (MI), in the absence of intact cells. It is not clear if these results are translatable to extracts from human BMC (hBMC) or mononuclear cells (hMNC), which would have significant clinical implications.

Pubmed ID: 22550548

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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