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A signal processing approach for enriched region detection in RNA polymerase II ChIP-seq data.

Zhi Han | Lu Tian | Thierry Pécot | Tim Huang | Raghu Machiraju | Kun Huang
BMC bioinformatics | 2012

RNA polymerase II (PolII) is essential in gene transcription and ChIP-seq experiments have been used to study PolII binding patterns over the entire genome. However, since PolII enriched regions in the genome can be very long, existing peak finding algorithms for ChIP-seq data are not adequate for identifying such long regions.

Pubmed ID: 22536865

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: U54 CA113001-06

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MCF-7 (tool)

RRID:CVCL_0031

Cell line MCF-7 is a Cancer cell line with a species of origin Homo sapiens (Human)

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