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Publication

Generation of 1E8 Single Chain Fv-Fc Construct Against Human CD59.

Jeong-Won Hong | Woon-Dong Cho | Kwon Pyo Hong | So-Seul Kim | Seung-Myoung Son | Seok-Joong Yun | Ho-Chang Lee | Sang-Soon Yoon | Hyung-Geun Song
Immune network | 2012

Therapeutic approaches using monoclonal antibodies (mAbs) against complement regulatory proteins (CRPs:i.e.,CD46,CD55 and CD59) have been reported for adjuvant cancer therapy. In this study, we generated a recombinant 1E8 single-chain anti-CD59 antibody (scFv-Fc) and tested anti-cancer effect.by using complement dependent cytotoxicity (CDC).

Pubmed ID: 22536168

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HEK293T (tool)

RRID:CVCL_0063

Cell line HEK293T is a Transformed cell line with a species of origin Homo sapiens (Human)

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