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Regulation of transcriptome, translation, and proteome in response to environmental stress in fission yeast.

Daniel H Lackner | Michael W Schmidt | Shuangding Wu | Dieter A Wolf | Jürg Bähler
Genome biology | 2012

Gene expression is controlled globally and at multiple levels in response to environmental stress, but the relationships among these dynamic regulatory changes are not clear. Here we analyzed global regulation during different stress conditions in fission yeast, Schizosaccharomyces pombe, combining dynamic genome-wide data on mRNA, translation, and protein profiles.

Pubmed ID: 22512868

Research resources used in this publication

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Antibodies used in this publication

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: RC2 CA148414
  • Agency: Wellcome Trust, United Kingdom
  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM059780
  • Agency: NIMH NIH HHS, United States
    Id: RC2 MH090011
  • Agency: NIGMS NIH HHS, United States
    Id: GM59780
  • Agency: NIGMS NIH HHS, United States
    Id: P50 GM085764
  • Agency: Cancer Research UK, United Kingdom

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This is a list of tools and resources that we have found mentioned in this publication.


ArrayExpress (tool)

RRID:SCR_002964

International functional genomics data collection generated from microarray or next-generation sequencing (NGS) platforms. Repository of functional genomics data supporting publications. Provides genes expression data for reuse to the research community where they can be queried and downloaded. Integrated with the Gene Expression Atlas and the sequence databases at the European Bioinformatics Institute. Contains a subset of curated and re-annotated Archive data which can be queried for individual gene expression under different biological conditions across experiments. Data collected to MIAME and MINSEQE standards. Data are submitted by users or are imported directly from the NCBI Gene Expression Omnibus.

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Origin (tool)

RRID:SCR_014212

Software application for data analysis and graphing. Origin contains a variety of different graph types, including statistical plots, 2D and 3D vector graphs, and counter graphs. More advance version is OriginPro which offers advanced analysis tools and Apps for Peak Fitting, Surface Fitting, Statistics and Signal Processing.

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