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Mechanisms involved in inhibition of chondrogenesis by activin-A.

Sho Mitsugi | Wataru Ariyoshi | Toshinori Okinaga | Takeshi Kaneuji | Yoshihiro Kataoka | Tetsu Takahashi | Tatsuji Nishihara
Biochemical and biophysical research communications | 2012

Activin-A, a member of the TGF-β family, is known to be present in bone and cartilage. Although, involvement of the TGF-β family in chondrogenesis has been reported, the mechanism by which activin-A regulates chondrogenesis has not been fully elucidated. The aim of this study was to investigate the effects of activin-A on chondrocyte differentiation in vitro.

Pubmed ID: 22425773

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