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Publication

SM934 treated lupus-prone NZB × NZW F1 mice by enhancing macrophage interleukin-10 production and suppressing pathogenic T cell development.

Li-Fei Hou | Shi-Jun He | Xin Li | Chun-Ping Wan | Yang Yang | Xiao-Hui Zhang | Pei-Lan He | Yu Zhou | Feng-Hua Zhu | Yi-Fu Yang | Ying Li | Wei Tang | Jian-Ping Zuo
PloS one | 2012

Artemisinin and its derivatives were reported to possess strong regulatory effects on inflammation and autoimmune diseases. This study was designed to examine the therapeutic effects and underlying mechanisms of SM934, a water-soluble artemisinin analogue, on lupus-prone female NZB × NZW F(1) mice.

Pubmed ID: 22389703

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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