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Seroprevalence of antibodies against Taenia solium cysticerci among refugees resettled in United States.

Seth E O'Neal | John M Townes | Patricia P Wilkins | John C Noh | Deborah Lee | Silvia Rodriguez | Hector H Garcia | William M Stauffer
Emerging infectious diseases | 2012

Neurocysticercosis (NCC) is a disease caused by central nervous system infection by the larval stage of the pork tapeworm, Taenia solium. In developing countries, NCC is a leading cause of adult-onset epilepsy. Case reports of NCC are increasing among refugees resettled to the United States and other nations, but the underlying prevalence among refugee groups is unknown. We tested stored serum samples from the Centers for Disease Control and Prevention Migrant Serum Bank for antibodies against T. solium cysts by using the enzyme-linked immunoelectrotransfer blot. Seroprevalence was high among all 4 populations tested: refugees from Burma (23.2%), Lao People's Democratic Republic (18.3%), Bhutan (22.8%), and Burundi (25.8%). Clinicians caring for refugee populations should suspect NCC in patients with seizure, chronic headache, or unexplained neurologic manifestations. Improved understanding of the prevalence of epilepsy and other associated diseases among refugees could guide recommendations for their evaluation and treatment before, during, and after resettlement.

Pubmed ID: 22377408

Research resources used in this publication

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Associated grants

  • Agency: Wellcome Trust, United Kingdom
  • Agency: Wellcome Trust, United Kingdom
    Id: 091077
  • Agency: FIC NIH HHS, United States
    Id: D43 TW001140
  • Agency: FIC NIH HHS, United States
    Id: R24 TW007988

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