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Publication

Neuregulin repellent signaling via ErbB4 restricts GABAergic interneurons to migratory paths from ganglionic eminence to cortical destinations.

Hao Li | Shen-Ju Chou | Tadashi Hamasaki | Carlos G Perez-Garcia | Dennis D M O'Leary
Neural development | 2012

Cortical GABAergic interneurons (INs) are generated in the medial ganglionic eminence (MGE) and migrate tangentially into cortex. Because most, if not all, migrating MGE-derived INs express the neuregulin (NRG) receptor, ErbB4, we investigated influences of Nrg1 isoforms and Nrg3 on IN migration through ventral telencephalon (vTel) and within cortex.

Pubmed ID: 22376909

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Associated grants

  • Agency: NIMH NIH HHS, United States
    Id: R01 MH086147
  • Agency: NINDS NIH HHS, United States
    Id: R01 NS031558
  • Agency: NINDS NIH HHS, United States
    Id: R01 NS31558

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Cell line HEK293T is a Transformed cell line with a species of origin Homo sapiens (Human)

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