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Smoking and adipose tissue inflammation suppress leptin expression in Japanese obese males: potential mechanism of resistance to weight loss among Japanese obese smokers.

Shintaro Nagayasu | Shigeki Suzuki | Akiko Yamashita | Ataru Taniguchi | Mitsuo Fukushima | Yoshikatsu Nakai | Kazuko Nin | Naoya Watanabe | Shoichiro Nagasaka | Daisuke Yabe | Fusanori Nishimura
Tobacco induced diseases | 2012

The effect of smoking on leptin regulation is controversial. Smoking may induce low-grade inflammation. Recent series of studies indicated the critical role of macrophage migration in the establishment of adipose tissue inflammation. In this study, we aimed to see the effects of smoking and inflammation on leptin regulation both at cellular and epidemiological levels.

Pubmed ID: 22373492

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RAW 264.7 (tool)

RRID:CVCL_0493

Cell line RAW 264.7 is a Cancer cell line with a species of origin Mus musculus

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3T3-L1 (tool)

RRID:CVCL_0123

Cell line 3T3-L1 is a Spontaneously immortalized cell line with a species of origin Mus musculus (Mouse)

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