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The Peru Urban versus Rural Asthma (PURA) Study: methods and baseline quality control data from a cross-sectional investigation into the prevalence, severity, genetics, immunology and environmental factors affecting asthma in adolescence in Peru.

Colin L Robinson | Lauren M Baumann | Robert H Gilman | Karina Romero | Juan Manuel Combe | Lilia Cabrera | Nadia N Hansel | Kathleen Barnes | Guillermo Gonzalvez | Robert A Wise | Patrick N Breysse | William Checkley
BMJ open | 2012

According to a large-scale international survey, Peru has one of the highest prevalences of asthma worldwide; however, data from this survey were limited to participants from urban Lima. The authors sought to characterise the epidemiology of asthma in Peru in two regions with disparate degrees of urbanisation. In this manuscript, the authors summarise the study design and implementation.

Pubmed ID: 22357570

Research resources used in this publication

None found

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Antibodies used in this publication

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Associated grants

  • Agency: NIEHS NIH HHS, United States
    Id: R01 ES018845
  • Agency: NHLBI NIH HHS, United States
    Id: HHSN268200900033C
  • Agency: FIC NIH HHS, United States
    Id: R24 TW007988
  • Agency: NIAID NIH HHS, United States
    Id: T35 AI065385
  • Agency: NHLBI NIH HHS, United States
    Id: K99 HL096955

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International HapMap Project (tool)

RRID:SCR_002846

THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. A multi-country collaboration among scientists and funding agencies to develop a public resource where genetic similarities and differences in human beings are identified and catalogued. Using this information, researchers will be able to find genes that affect health, disease, and individual responses to medications and environmental factors. All of the information generated by the Project will be released into the public domain. Their goal is to compare the genetic sequences of different individuals to identify chromosomal regions where genetic variants are shared. Public and private organizations in six countries are participating in the International HapMap Project. Data generated by the Project can be downloaded with minimal constraints. HapMap project related data, software, and documentation include: bulk data on genotypes, frequencies, LD data, phasing data, allocated SNPs, recombination rates and hotspots, SNP assays, Perlegen amplicons, raw data, inferred genotypes, and mitochondrial and chrY haplogroups; Generic Genome Browser software; protocols and information on assay design, genotyping and other protocols used in the project; and documentation of samples/individuals and the XML format used in the project.

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Illumina (tool)

RRID:SCR_010233

American company incorporated that develops, manufactures and markets integrated systems for the analysis of genetic variation and biological function. Provides a line of products and services that serve the sequencing, genotyping and gene expression and proteomics markets. Its headquarters are located in San Diego, California.

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