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Publication

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers.

Antonis C Antoniou | Karoline B Kuchenbaecker | Penny Soucy | Jonathan Beesley | Xiaoqing Chen | Lesley McGuffog | Andrew Lee | Daniel Barrowdale | Sue Healey | Olga M Sinilnikova | Maria A Caligo | Niklas Loman | Katja Harbst | Annika Lindblom | Brita Arver | Richard Rosenquist | Per Karlsson | Kate Nathanson | Susan Domchek | Tim Rebbeck | Anna Jakubowska | Jan Lubinski | Katarzyna Jaworska | Katarzyna Durda | Elżbieta Złowowcka-Perłowska | Ana Osorio | Mercedes Durán | Raquel Andrés | Javier Benítez | Ute Hamann | Frans B Hogervorst | Theo A van Os | Senno Verhoef | Hanne E J Meijers-Heijboer | Juul Wijnen | Encarna B Gómez Garcia | Marjolijn J Ligtenberg | Mieke Kriege | J Margriet Collée | Margreet G E M Ausems | Jan C Oosterwijk | Susan Peock | Debra Frost | Steve D Ellis | Radka Platte | Elena Fineberg | D Gareth Evans | Fiona Lalloo | Chris Jacobs | Ros Eeles | Julian Adlard | Rosemarie Davidson | Trevor Cole | Jackie Cook | Joan Paterson | Fiona Douglas | Carole Brewer | Shirley Hodgson | Patrick J Morrison | Lisa Walker | Mark T Rogers | Alan Donaldson | Huw Dorkins | Andrew K Godwin | Betsy Bove | Dominique Stoppa-Lyonnet | Claude Houdayer | Bruno Buecher | Antoine de Pauw | Sylvie Mazoyer | Alain Calender | Mélanie Léoné | Brigitte Bressac-de Paillerets | Olivier Caron | Hagay Sobol | Marc Frenay | Fabienne Prieur | Sandra U Ferrer | Isabelle Mortemousque | Saundra Buys | Mary Daly | Alexander Miron | Mary U Terry | John L Hopper | Esther M John | Melissa Southey | David Goldgar | Christian F Singer | Anneliese Fink-Retter | Muy-Kheng Tea | Daphne U Kaulich | Thomas V Hansen | Finn C Nielsen | Rosa B Barkardottir | Mia Gaudet | Tomas Kirchhoff | Vijai Joseph | Ana Dutra-Clarke | Kenneth Offit | Marion Piedmonte | Judy Kirk | David Cohn | Jean Hurteau | John Byron | James Fiorica | Amanda E Toland | Marco Montagna | Cristina Oliani | Evgeny Imyanitov | Claudine Isaacs | Laima Tihomirova | Ignacio Blanco | Conxi Lazaro | Alex Teulé | J Del Valle | Simon A Gayther | Kunle Odunsi | Jenny Gross | Beth Y Karlan | Edith Olah | Soo-Hwang Teo | Patricia A Ganz | Mary S Beattie | Cecelia M Dorfling | Elizabeth U van Rensburg | Orland Diez | Ava Kwong | Rita K Schmutzler | Barbara Wappenschmidt | Christoph Engel | Alfons Meindl | Nina Ditsch | Norbert Arnold | Simone Heidemann | Dieter Niederacher | Sabine Preisler-Adams | Dorothea Gadzicki | Raymonda Varon-Mateeva | Helmut Deissler | Andrea Gehrig | Christian Sutter | Karin Kast | Britta Fiebig | Dieter Schäfer | Trinidad Caldes | Miguel de la Hoya | Heli Nevanlinna | Taru A Muranen | Bernard Lespérance | Amanda B Spurdle | Susan L Neuhausen | Yuan C Ding | Xianshu Wang | Zachary Fredericksen | Vernon S Pankratz | Noralane M Lindor | Paolo Peterlongo | Siranoush Manoukian | Bernard Peissel | Daniela Zaffaroni | Bernardo Bonanni | Loris Bernard | Riccardo Dolcetti | Laura Papi | Laura Ottini | Paolo Radice | Mark H Greene | Jennifer T Loud | Irene L Andrulis | Hilmi Ozcelik | Anna U Mulligan | Gord Glendon | Mads Thomassen | Anne-Marie Gerdes | Uffe B Jensen | Anne-Bine Skytte | Torben A Kruse | Georgia Chenevix-Trench | Fergus J Couch | Jacques Simard | Douglas F Easton | CIMBA, SWE-BRCA | HEBON | EMBRACE | GEMO Collaborators Study | kConFab Investigators
Breast cancer research : BCR | 2012

Several common alleles have been shown to be associated with breast and/or ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. Recent genome-wide association studies of breast cancer have identified eight additional breast cancer susceptibility loci: rs1011970 (9p21, CDKN2A/B), rs10995190 (ZNF365), rs704010 (ZMIZ1), rs2380205 (10p15), rs614367 (11q13), rs1292011 (12q24), rs10771399 (12p11 near PTHLH) and rs865686 (9q31.2).

Pubmed ID: 22348646

Research resources used in this publication

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: CA116201
  • Agency: NCI NIH HHS, United States
    Id: CA128978
  • Agency: NCI NIH HHS, United States
    Id: P30-CA051008
  • Agency: NCI NIH HHS, United States
    Id: CA- 06-503
  • Agency: Cancer Research UK, United Kingdom
    Id: C12292/A11174
  • Agency: Cancer Research UK, United Kingdom
    Id: 11174
  • Agency: NCI NIH HHS, United States
    Id: R01 CA128978
  • Agency: NCI NIH HHS, United States
    Id: P30 CA051008
  • Agency: NCI NIH HHS, United States
    Id: P50 CA116201
  • Agency: NCI NIH HHS, United States
    Id: U01 CA69398
  • Agency: NCI NIH HHS, United States
    Id: U01 CA69638
  • Agency: Cancer Research UK, United Kingdom
    Id: 10118
  • Agency: NCI NIH HHS, United States
    Id: R01 CA74415
  • Agency: NCI NIH HHS, United States
    Id: U01 CA69417
  • Agency: Cancer Research UK, United Kingdom
    Id: C5047/A8385
  • Agency: NCI NIH HHS, United States
    Id: RFA-CA-06-503
  • Agency: NCI NIH HHS, United States
    Id: U01 CA69446
  • Agency: NCI NIH HHS, United States
    Id: U01 CA69631
  • Agency: Cancer Research UK, United Kingdom
    Id: C1287/A11990
  • Agency: Cancer Research UK, United Kingdom
    Id: 11022
  • Agency: Cancer Research UK, United Kingdom
    Id: C1287/A10118
  • Agency: NCI NIH HHS, United States
    Id: U01 CA69467

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This is a list of tools and resources that we have found mentioned in this publication.

MENDEL (tool)

RRID:SCR_009288

Software application for genetic analysis of human pedigree data under models involving a small number of loci. MENDEL is useful for segregation analysis, linkage calculations, genetic counseling, allele frequency estimation, and related kinds of problems. (entry from Genetic Analysis Software)

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