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Application of reticulated platelets to transfusion management during autologous stem cell transplantation.

Sergio Parco | Fulvia Vascotto
OncoTargets and therapy | 2012

The immature (or reticulated) platelet fraction (IPF) is rich in nucleic acids, especially RNA, and can be used as a predictive factor for platelet recovery in platelet immunomediated consumption or in postchemotherapy myelosuppression. Our aim was to determine if transfusions with IPF-rich solutions, during autologous peripheral blood stem cell transplantation, reduce the occurrence of bleeding and hemorrhagic complications.

Pubmed ID: 22334789

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