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Publication

Noninvasive near-infrared live imaging of human adult mesenchymal stem cells transplanted in a rodent model of Parkinson's disease.

P Bossolasco | L Cova | G Levandis | V Diana | S Cerri | G Lambertenghi Deliliers | E Polli | V Silani | F Blandini | M T Armentero
International journal of nanomedicine | 2012

We have previously shown that human mesenchymal stem cells (hMSCs) can reduce toxin-induced neurodegeneration in a well characterized rodent model of Parkinson's disease. However, the precise mechanisms, optimal cell concentration required for neuroprotection, and detailed cell tracking need to be defined. We exploited a near-infrared imaging platform to perform noninvasive tracing following transplantation of tagged hMSCs in live parkinsonian rats.

Pubmed ID: 22334776

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