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Publication

Acquisition of EMT phenotype in the gefitinib-resistant cells of a head and neck squamous cell carcinoma cell line through Akt/GSK-3β/snail signalling pathway.

S Maseki | K Ijichi | H Tanaka | M Fujii | Y Hasegawa | T Ogawa | S Murakami | E Kondo | H Nakanishi
British journal of cancer | 2012

Epithelial mesenchymal transition (EMT) is known to be associated with chemoresistance as well as increased invasion/metastasis. However, the relationship between EMT and resistance to an epidermal growth factor receptor (EGFR) -targeting drug in head and neck squamous cell carcinoma (HNSCC) remains unknown. In this study, we investigated the acquisition of EMT by gefitinib in HNSCC cell line (UMSCC81B).

Pubmed ID: 22315058

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Crl:NU(NCr)-Foxn1nu (tool)

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Mus musculus with name Crl:NU(NCr)-Foxn1nu from IMSR.

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