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RNAa-mediated overexpression of WT1 induces apoptosis in HepG2 cells.

Qi Qin | Yi-Wei Lin | Xiang-Yi Zheng | Hong Chen | Qi-Qi Mao | Kai Yang | Shou-Jiang Huang | Zheng-Yan Zhao
World journal of surgical oncology | 2012

Recent studies have reported that double-stranded RNA (dsRNA) can activate gene expression by targeting promoter sequence in a process termed RNA activation. The present study was conducted to evaluate the potential of WT1 induction by small activating RNA targeting the WT1 promoter (dsWT1) in the treatment of hepatocellular carcinoma.

Pubmed ID: 22244202

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Hep-G2 (tool)

RRID:CVCL_0027

Cell line Hep-G2 is a Cancer cell line with a species of origin Homo sapiens (Human)

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