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Relationship of increased aurora kinase A gene copy number, prognosis and response to chemotherapy in patients with metastatic colorectal cancer.

E Dotan | N J Meropol | F Zhu | F Zambito | B Bove | K Q Cai | A K Godwin | E A Golemis | I Astsaturov | S J Cohen
British journal of cancer | 2012

Increased Aurora kinase A gene copy number (AURKA-CN) has been reported in metastatic colorectal cancer (mCRC), with unknown relationship to clinical outcome. We correlated increased AURKA-CN in mCRC tumours with KRAS mutation status, overall and progression-free survival (OS, PFS).

Pubmed ID: 22240781

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: P30 CA006927
  • Agency: NCI NIH HHS, United States
    Id: R01 CA063366
  • Agency: NCI NIH HHS, United States
    Id: R01CA63366
  • Agency: NCI NIH HHS, United States
    Id: 3P30CA006927-47S4

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Caco-2 (tool)

RRID:CVCL_0025

Cell line Caco-2 is a Cancer cell line with a species of origin Homo sapiens (Human)

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HCT 116 (tool)

RRID:CVCL_0291

Cell line HCT 116 is a Cancer cell line with a species of origin Homo sapiens (Human)

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