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Differential expression patterns of conserved miRNAs and isomiRs during Atlantic halibut development.

Teshome T Bizuayehu | Carlos F C Lanes | Tomasz Furmanek | Bård O Karlsen | Jorge M O Fernandes | Steinar D Johansen | Igor Babiak
BMC genomics | 2012

MicroRNAs (miRNAs) play a major role in animal ontogenesis. Size variants of miRNAs, isomiRs, are observed along with the main miRNA types, but their origin and possible biological role are uncovered yet. Developmental profiles of miRNAs have been reported in few fish species only and, to our knowledge, differential expressions of isomiRs have not yet been shown during fish development. Atlantic halibut, Hippoglossus hippoglossus L., undergoes dramatic metamorphosis during early development from symmetrical pelagic larval stage to unsymmetrical flatfish. No data exist on role of miRNAs in halibut metamorphosis.

Pubmed ID: 22233483

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miRBase (tool)

RRID:SCR_003152

Central online repository for microRNA nomenclature, sequence data, annotation and target prediction.Collection of published miRNA sequences and annotation.

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