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The microRNA miR-8 is a positive regulator of pigmentation and eclosion in Drosophila.

Jennifer A Kennell | Ken M Cadigan | Iryna Shakhmantsir | Evan J Waldron
Developmental dynamics : an official publication of the American Association of Anatomists | 2012

MicroRNAs (miRNAs) are short, non-coding RNAs that post-transcriptionally silence gene expression by binding to target mRNAs. Previous studies have identified the miRNA miR-8 as a pleiotropic regulator of Drosophila development, controlling body size and neuronal survival by targeting multiple mRNAs. In this study we demonstrate that miR-8 is also required for proper spatial patterning of pigment on the adult abdominal cuticle in females but not males.

Pubmed ID: 22174085

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Associated grants

  • Agency: NIGMS NIH HHS, United States
    Id: F32 GM074465
  • Agency: NIGMS NIH HHS, United States
    Id: F32 GM074465-03
  • Agency: NIGMS NIH HHS, United States
    Id: F32GM074465

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RRID:SCR_010263

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