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The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function.

L-M Holbrook | P Sasikumar | R G Stanley | A D Simmonds | A B Bicknell | J M Gibbins
Journal of thrombosis and haemostasis : JTH | 2012

Thiol isomerases are a family of endoplasmic reticulum enzymes which orchestrate redox-based modifications of protein disulphide bonds. Previous studies have identified important roles for the thiol isomerases PDI and ERp5 in the regulation of normal platelet function.

Pubmed ID: 22168334

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Associated grants

  • Agency: Medical Research Council, United Kingdom
    Id: G0701399
  • Agency: British Heart Foundation, United Kingdom

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SlideBook (tool)

RRID:SCR_014423

Digital microscopy software for research microscopy. It comes standard with drivers to control numerous instruments in and around the microscope. When online, data is acquired in a native-3D format over time, color and specimen locations in customizable experiment protocols. Data can be analyzed by a wide variety of tools for image processing including mathematical operations, statistics functions, analysis scripting and import to/export from MATLAB. Additional modules are available for special applications ranging from deconvolution to photomanipulation to multiphoton.

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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