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Characterization of 4-[18F]-ADAM as an imaging agent for SERT in non-human primate brain using PET: a dynamic study.

Yu-An Chen | Wen-Sheng Huang | Yaoh-Shiang Lin | Cheng-Yi Cheng | Ren-Shyan Liu | Shyh-Jen Wang | I-Hsun Li | San-Yuan Huang | Chyng-Yann Shiue | Cheng-Yu Chen | Kuo-Hsing Ma
Nuclear medicine and biology | 2012

Serotonin transporter (SERT) has been associated with many psychiatric diseases. This study investigated the biodistribution of a serotonin transporter imaging agent, N,N-dimethyl-2-(2-amino-4-(18)F-fluorophenylthio)benzylamine (4-[(18)F]-ADAM), in nonhuman primate brain using positron emission tomography (PET).

Pubmed ID: 22136885

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PMOD Software (tool)

RRID:SCR_016547

Software environment for the quantification of biomedical images. Biomedical image processing, analysis, and modeling software. Consists of set of tools for kinetic modeling, parametric mapping, image registration, 3D rendering and pattern analysis. Used for quantification of PET data. Many quantification methods are generic and can be applied to other modalities such as SPECT, MR and CT.

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