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Publication

Automated bone volume and thickness measurements in small animal whole-body MicroCT data.

Martin Baiker | Thomas J A Snoeks | Eric L Kaijzel | Ivo Que | Jouke Dijkstra | Boudewijn P F Lelieveldt | Clemens W G M Löwik
Molecular imaging and biology | 2012

Quantification of osteolysis is crucial for monitoring treatment effects in preclinical research and should be based on MicroCT data rather than conventional 2D radiographs to obtain optimal accuracy. However, data assessment is greatly complicated in the case of 3D data. This paper presents an automated method to follow osteolytic lesions quantitatively and visually over time in whole-body MicroCT data of mice.

Pubmed ID: 21993834

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