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The brain mechanisms of cognitive-behavioral therapy (CBT), a highly effective treatment for pediatric obsessive-compulsive disorder (OCD), are unknown. Neuroimaging in adult OCD indicates that CBT is associated with metabolic changes in striatum, thalamus, and anterior cingulate cortex. We therefore probed putative metabolic effects of CBT on these brain structures in pediatric OCD using proton magnetic resonance spectroscopic imaging (1H MRSI).
Pubmed ID: 21983143
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Software for automatic quantification of in vivo proton MR spectra. Though it is mainly used for brain analysis, it can be used for a variety of analyses in different areas of the body. It receives time-domain data as input and gives a one page summary output. It is fully automatic, non-interactive, and operator-independent.
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