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LATS2, which encodes a novel serine/threonine kinase, is known to be important in centrosome duplication and in the maintenance of genomic stability. Recently, a potential role for LATS2 in cancer has been reported. In breast cancer and acute lymphoblastic leukemia (ALL), LATS2 mRNA is downregulated and has been suggested to be a tumor suppressor. However, the role of LATS2 in nasopharyngeal carcinoma has not been investigated. In this study, we aimed to investigate the expression pattern of LATS2 and its clinicopathological involvement in nasopharyngeal carcinoma to understand its effect on cell survival.
Pubmed ID: 20932276
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Cell line CNE-1 is a Hybrid cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line C666-1 is a Cancer cell line with a species of origin Homo sapiens (Human)
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