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A functional melanocortin system may be required for chronic CNS-mediated antidiabetic and cardiovascular actions of leptin.

Alexandre A da Silva | Jussara M do Carmo | J Nathan Freeman | Lakshmi S Tallam | John E Hall
Diabetes | 2009

We recently showed that leptin has powerful central nervous system (CNS)-mediated antidiabetic and cardiovascular actions. This study tested whether the CNS melanocortin system mediates these actions of leptin in diabetic rats.

Pubmed ID: 19491210

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Associated grants

  • Agency: NHLBI NIH HHS, United States
    Id: P01 HL051971
  • Agency: NHLBI NIH HHS, United States
    Id: P01HL-51971

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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