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Microparticle-induced release of B-lymphocyte regulators by rheumatoid synoviocytes.

Laurent Messer | Ghada Alsaleh | Jean-Marie Freyssinet | Fatiha Zobairi | Isabelle Leray | Jacques-Eric Gottenberg | Jean Sibilia | Florence Toti-Orfanoudakis | Dominique Wachsmann
Arthritis research & therapy | 2009

In the present study, we investigated the ability of microparticles isolated from synovial fluids from patients with rheumatoid arthritis or osteoarthritis to induce the synthesis and release of key cytokines of B-lymphocyte modulation such as B cell-activating factor, thymic stroma lymphopoietin, and secretory leukocyte protease inhibitor by rheumatoid fibroblast-like synoviocytes.

Pubmed ID: 19291304

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THP-1 (tool)

RRID:CVCL_0006

Cell line THP-1 is a Cancer cell line with a species of origin Homo sapiens (Human)

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