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Publication

Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-alpha mice.

Soner Dogan | Xin Hu | Yan Zhang | Nita J Maihle | Joseph P Grande | Margot P Cleary
Breast cancer research : BCR | 2007

Obesity is a risk factor for postmenopausal breast cancer and is associated with shortened mammary tumor (MT) latency in MMTV-TGF-alpha mice with dietary-induced obesity. One link between obesity and breast cancer is the adipokine, leptin. Here, the focus is on diet-induced obesity and MT and mammary fat pad (MFP) leptin and apoptotic signaling proteins.

Pubmed ID: 18162139

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: CA079808
  • Agency: NCI NIH HHS, United States
    Id: R01 CA079808
  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK016105
  • Agency: NCI NIH HHS, United States
    Id: CA101858
  • Agency: NCI NIH HHS, United States
    Id: R01 CA101858
  • Agency: NIDDK NIH HHS, United States
    Id: DK16105

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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