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Evolutionary dynamics of eukaryotic selenoproteomes: large selenoproteomes may associate with aquatic life and small with terrestrial life.

Alexey V Lobanov | Dmitri E Fomenko | Yan Zhang | Aniruddha Sengupta | Dolph L Hatfield | Vadim N Gladyshev
Genome biology | 2007

Selenocysteine (Sec) is a selenium-containing amino acid that is co-translationally inserted into nascent polypeptides by recoding UGA codons. Selenoproteins occur in both eukaryotes and prokaryotes, but the selenoprotein content of organisms (selenoproteome) is highly variable and some organisms do not utilize Sec at all.

Pubmed ID: 17880704

Research resources used in this publication

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Associated grants

  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM061603
  • Agency: NIGMS NIH HHS, United States
    Id: GM061603

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DOE Joint Genome Institute (tool)

RRID:SCR_003045

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RRID:SCR_011819

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