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Publication

Dynamic evolution of selenocysteine utilization in bacteria: a balance between selenoprotein loss and evolution of selenocysteine from redox active cysteine residues.

Yan Zhang | Hector Romero | Gustavo Salinas | Vadim N Gladyshev
Genome biology | 2006

Selenocysteine (Sec) is co-translationally inserted into protein in response to UGA codons. It occurs in oxidoreductase active sites and often is catalytically superior to cysteine (Cys). However, Sec is used very selectively in proteins and organisms. The wide distribution of Sec and its restricted use have not been explained.

Pubmed ID: 17054778

Research resources used in this publication

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Additional research tools detected in this publication

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Associated grants

  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM061603
  • Agency: NIGMS NIH HHS, United States
    Id: GM061603

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This is a list of tools and resources that we have found mentioned in this publication.

TBLASTN (tool)

RRID:SCR_011822

Tool to search translated nucleotide databases using a protein query.

View all literature mentions

PhyML (tool)

RRID:SCR_014629

Web phylogeny server based on the maximum-likelihood principle.

View all literature mentions

ClustalW (tool)

RRID:SCR_017277

Web sevice of ClustalW provided by DNA data bank of Japan.

View all literature mentions

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