On page 1 showing 1 ~ 20 out of 42 results
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Wistar
Assessments: Neuron-Specific Enolase Light Immuno Assay
Citation: Woertgen C, Rothoerl RD, Brawanski A. Neuron-specific enolase serum levels after controlled cortical impact injury in the ratJ Neurotrauma. 2001 May;18(5):569-73. doi: 10.1089\/089771501300227378.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Immunohistochemistry (IHC), Magnetic resonance imaging (MRI)
Citation: Tu TW, Lescher JD, Williams RA, Jikaria N, Turtzo LC, Frank JA. Abnormal Injury Response in Spontaneous Mild Ventriculomegaly Wistar Rat Brains: A Pathological Correlation Study of Diffusion Tensor and Magnetization Transfer Imaging in Mild Traumatic Brain InjuryJ Neurotrauma. 2017 Jan 1;34(1):248-256. doi: 10.1089\/neu.2015.4355. Epub 2016 Apr 11. PMC5198143
TBI Model Type: Fluid percussion injury model
Organism Species: rat
Organism Strain: Wistar
Assessments: Diffusion Tensor Imaging scan, Neurological Severity Score (NSS)
Citation: Nakuci J, McGuire M, Schweser F, Poulsen D, Muldoon SF. Differential Patterns of Change in Brain Connectivity Resulting from Severe Traumatic Brain InjuryBrain Connect. 2022 May 5. doi: 10.1089\/brain.2021.0168. Online ahead of print.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Accelerometer measurement, Immunohistochemistry (IHC)
Citation: Viano DC, Hamberger A, Bolouri H, Säljö A. Evaluation of three animal models for concussion and serious brain injuryAnn Biomed Eng. 2012 Jan;40(1):213-26. doi: 10.1007\/s10439-011-0386-2. Epub 2011 Oct 20.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: modified Neurological Severity Score (mNSS), Neurological examination, Sensorimotor examination, Nissl staining, light/dark anxiety transition test, conditioned passive avoidance response, elevated plus-maze, histology, Hematoxylin and Eosin
Citation: Plekhova NG, Radkov IV, Zinoviev SV, Dyuizen IV, Baryshev AN, Shumatov VB. Effect of Mild Traumatic Brain Injury on Behavioral Reactions and Neocortical Morphology in RatsBull Exp Biol Med. 2021 Mar;170(5):672-676. doi: 10.1007\/s10517-021-05130-6. Epub 2021 Mar 31.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Object Recognition Memory Test, Open-Field Test, Western blot, Brain Water Content, qRT-PCR
Citation: Furtado ABV, Gonçalves DF, Hartmann DD, Courtes AA, Cassol G, Nunez-Figueredo Y, Argolo DS, do Nascimento RP, Costa SL, da Silva VDA, Royes LFF, Soares FAA. JM-20 Treatment After Mild Traumatic Brain Injury Reduces Glial Cell Pro-inflammatory Signaling and Behavioral and Cognitive Deficits by Increasing Neurotrophin ExpressionMol Neurobiol. 2021 Sep;58(9):4615-4627. doi: 10.1007\/s12035-021-02436-4. Epub 2021 Jun 19.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Brain water content, Western blot
Citation: Lu KT, Huang TC, Tsai YH, Yang YL. Transient receptor potential vanilloid type 4 channels mediate Na-K-Cl-co-transporter-induced brain edema after traumatic brain injuryJ Neurochem. 2017 Mar;140(5):718-727. doi: 10.1111\/jnc.13920.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Brain water content, Hematoxylin and Eosin, qRT-PCR, Western blot, Neurological Severity Score (NSS), TUNEL staining
Citation: Li Z, Wang Y, Zeng G, Zheng X, Wang W, Ling Y, Tang H, Zhang J. Increased miR-155 and heme oxygenase-1 expression is involved in the protective effects of formononetin in traumatic brain injury in ratsAm J Transl Res. 2017 Dec 15;9(12):5653-5661. eCollection 2017. PMC5752915
TBI Model Type: Fluid percussion injury model
Organism Species: rat
Organism Strain: Wistar
Assessments: Cell Morphology
Citation: Gupta A, Dovek L, Proddutur A, Elgammal FS, Santhakumar V. Long-Term Effects of Moderate Concussive Brain Injury During Adolescence on Synaptic and Tonic GABA Currents in Dentate Granule Cells and Semilunar Granule CellsFront Neurosci. 2022 Mar 14;16:800733. doi: 10.3389\/fnins.2022.800733. eCollection 2022. PMC8964009
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: High resolution respirometry, Mitochondrial respiration assay, object recognition test, open field test, Rotarod test
Citation: Courtes AA, Gonçalves DF, Hartmann DD, da Rosa PC, Cassol G, Royes LFF, de Carvalho NR, Soares FAA. Guanosine protects against behavioural and mitochondrial bioenergetic alterations after mild traumatic brain injuryBrain Res Bull. 2020 Oct;163:31-39. doi: 10.1016\/j.brainresbull.2020.07.003. Epub 2020 Jul 15.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: magnetic resonance imaging
Citation: Braeckman K, Descamps B, Vanhove C.Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain InjuryJ Vis Exp. 2019 Aug 14;(150). doi: 10.3791/60012.10.3791/60012
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Dark neuron, Terminal deoxynucleotidyl transferase-mediated biotinylated dUTP nick-end labeling, Western blotting, modified Neurological Severity Score, western blot
Citation: Ghadiri T, Vakilzadeh G, Hajali V, Khodagholi F.Progesterone modulates post-traumatic epileptogenesis through regulation of BDNF-TrkB signaling and cell survival-related pathways in the rat hippocampusNeurosci Lett. 2019 Sep 14;709:134384. doi: 10.1016/j.neulet.2019.134384. Epub 2019 Jul 17.10.1016/j.neulet.2019.134384
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Lipid peroxidation assay, Quantitative real-time polymarase chain reaction
Citation: Emir M, Ozisik K, Cagli K, Misirlioglu M, Ozisik P, Iscan Z, Yildirim E, Kilinc K, Sener E.Effect of erythropoietin on bcl-2 gene expression in rat cardiac myocytes after traumatic brain injuryTransplant Proc. 2004 Dec;36(10):2935-8. doi: 10.1016/j.transproceed.2004.11.101.10.1016/j.transproceed.2004.11.101
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Nissl and TTC stained, Nissl staining, lesion volume, modified Neurologic Severity Score, open field behavioral test, western blot analysis
Citation: Ghadiri T, Sharifzadeh M, Khodagholi F, Modarres Mousavi SM, Hassanzadeh G, Zarrindast MR, Gorji A.A novel traumatic brain injury model for induction of mild brain injury in rats.J Neurosci Methods. 2014 Aug 15;233:18-27. doi: 10.1016/j.jneumeth.2014.05.035. Epub 2014 Jun 4.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Citation: Koizumi H, Fujisawa H, Ito H, Maekawa T, Di X, Bullock R.Effects of mild hypothermia on cerebral blood flow-independent changes in cortical extracellular levels of amino acids following contusion trauma in the ratBrain Res. 1997 Feb 7;747(2):304-12. doi: 10.1016/s0006-8993(96)01240-1.10.1016/s0006-8993(96)01240-1
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: ELISA, H & E staining, Luxol fast blue staining, Nogo-A mRNA assay, RT-PCR, Water content, Western blot analysis
Citation: Chao PK, Lu KT, Jhu JY, Wo YY, Huang TC, Ro LS, Yang YL.Indomethacin protects rats from neuronal damage induced by traumatic brain injury and suppresses hippocampal IL-1β release through the inhibition of Nogo-A expressionJ Neuroinflammation. 2012 Jun 7;9:121. doi: 10.1186/1742-2094-9-121.PMC341669510.1186/1742-2094-9-121
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Immunohistochemical, Neurologic Severity Scores, ematoxylin-eosin staining, hematoxylin-eosin staining
Citation: Bonilla C, Zurita M, Otero L, Aguayo C, Rico MA, Vaquero J.The severity of brain damage determines bone marrow stromal cell therapy efficacy in a traumatic brain injury modelJ Trauma Acute Care Surg. 2012 May;72(5):1203-12; discussion 1211-2. doi: 10.1097/TA.0b013e318248bdcf.10.1097/TA.0b013e318248bdcf
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: CatWalk system, modified neurological severity scores
Citation: Zhang R, Qin K, Fa Z, Liu Y, Li P, Cai Y, Jiang X.[Motor function evaluation in rats receiving umbilical cord mesenchymal stromal cell transplantation for traumatic brain injury using CatWalk automated gait analysis system]Nan Fang Yi Ke Da Xue Xue Bao. 2012 Apr;32(4):449-55.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Intracranial pressure monitoring, Blood gas analysis, Hematocrit testing, Cerebral blood flow
Citation: Kahveci FS, Kahveci N, Alkan T, Goren B, Korfali E, Ozluk K.Surg Neurol. 2001 Sep;56(3):206-14. doi: 10.1016/s0090-3019(01)00555-9.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Rotarod test, modified Neurologic Severity Score (mNSS), Immunofluorescence, Hematoxylin and eosin, Immunohistochemistry (IHC)
Citation: Bonilla C, Zurita M, Otero L, Aguayo C, Vaquero J.Brain Inj. 2009 Aug;23(9):760-9. doi: 10.1080/02699050903133970.
