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The effect of traumatic brain injury upon the concentration and expression of interleukin-1beta and interleukin-10 in the rat.

K Kamm | W Vanderkolk | C Lawrence | M Jonker | AT Davis
The Journal of trauma | 2006 Jan

Using a model of traumatic brain injury (TBI) in the rat, this study was undertaken to characterize the short-term biochemical changes of IL-1beta, IL-10, and tumor necrosis factor TNF-alpha to determine whether injury in the brain elicits a systemic cytokine response.

Pubmed ID: 16456449

TBI Model

    • Animal Information

  • Species: rat
  • Strain: Sprague-Dawley
  • Age (weeks): No age reported
  • Weight (grams): 350 - 375

    • Assessments

    ELISA, reverse-transcriptase polymerase chain reaction

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    University of California, San Diego





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