Searching across hundreds of databases

Our searching services are busy right now. Please try again later

  • Register
X
Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

X

Leaving Community

Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.

No
Yes

NMDA receptor antagonist MK-801 reduces neuronal damage and preserves learning and memory in a rat model of traumatic brain injury.

RZ Han | JJ Hu | YC Weng | DF Li | Y Huang
Neuroscience bulletin | 2009 Dec

NMDA receptor channel plays an important role in the pathophysiological process of traumatic brain injury (TBI). The present study aims to study the pathological mechanism of TBI and the impairment of learning and memory after TBI, and to investigate the mechanism of the protective effect of NMDA receptor antagonist MK-801 on learning and memory disorder after TBI.

Pubmed ID: 19927173

TBI Model

  • Weight-drop model
  • Weight-drop

    • Animal Information

  • Species: rat
  • Strain: Shang-hai Jiaotong University
  • Age (weeks): No age reported
  • Weight (grams): 270 - 230

    • Assessments

    Behavior test, Morphological and immunohistochemical assays, Navigational test, Probe test

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

    Recent News Entries

    Contact Us

    Department of Neurosciences, School of Medicine

    University of California, San Diego





    About SciCrunch | Privacy Policy | Terms of Service

    SciCrunch