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Evaluation of PECAM-1 and p38 MAPK expressions in cerebellum tissue of rats treated with caffeic acid phenethyl ester: a biochemical and immunohistochemical study.

A Çetin | E Deveci
Folia morphologica | 2019

This study aimed to investigate the antioxidative and anti-inflam- matory effects of caffeic acid phenethyl ester (CAPE) on damage caused to cere- bellum tissue by diffuse traumatic head trauma via biochemical, histopathologic, and immuno-histochemical methods.

Pubmed ID: 30543083

TBI Model

  • Weight-drop model
  • Diffuse brain injury model

    • Animal Information

  • Species: rat
  • Strain: Sprague-Dawley
  • Age (weeks): No age reported
  • Weight (grams): 300 - 350

    • Assessments

    Malondialdehyde and glutathione peroxidase ­ assays, Immunohistochemistry, haematoxylin, superoxide dismutase activity, catalase activity, Statistical analysis

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Department of Neurosciences, School of Medicine

    University of California, San Diego





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