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Acid Sphingomyelinase Inhibition Mitigates Histopathological and Behavioral Changes in a Murine Model of Traumatic Brain Injury.

GM Niziolek | RM Boudreau | J Baker | LA Friend | AT Makley | MJ Edwards | E Gulbins | MD Goodman
Journal of neurotrauma | 2020 Sep 01

Pubmed ID: 32138594

TBI Model

  • Weight-drop model
  • Weight-drop

    • Animal Information

  • Species: mouse
  • Strain: C57BL6/J
  • Age (weeks): 8 - 10
  • Weight (grams): No weight reported

    • Assessments

    Neuropsychiatric, Rotarod, forced swim test, immunohistochemistry

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Contact Us

    Department of Neurosciences, School of Medicine

    University of California, San Diego





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