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Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury.

H Wang | XM Zhou | LY Wu | GJ Liu | WD Xu | XS Zhang | YY Gao | T Tao | Y Zhou | Y Lu | J Wang | CL Deng | Z Zhuang | CH Hang | W Li
Journal of neuroinflammation | 2020 Jun 15

Pubmed ID: 32539839

TBI Model

  • Weight-drop model
  • Weight-drop
  • Animal Information

  • Species: mouse
  • Strain: C57BL/6
  • Age (weeks): No age reported
  • Weight (grams): 25 - 30
  • Assessments

    Brain water content, M29, 79-dichlorodihydrofluorescein diacetate (DCFH-DA) staining, Morris Water Maze, Neurological Severity Scores, Nissl staining, TdT-mediated dUTP Nick-End Labeling, We performed modified Neurological Severity Scores (mNSS), rotarod test, and Morris Water Maze (MWM) test, respectively (n = 8 for each group), enzyme linked immunosorbent assay, immunofluorescence, immunohistochemistry, quantitative real time polymerase chain reaction, rotarod test, western blot

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available
  • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available