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Plasticity of the contralateral motor cortex following focal traumatic brain injury in the rat.

HW Axelson | T Winkler | J Flygt | A Djupsjö | A Hånell | N Marklund
Restorative neurology and neuroscience | 2013

Recovery is limited following traumatic brain injury (TBI) since injured axons regenerate poorly and replacement of lost cells is minimal. Behavioral improvements could instead be due to plasticity of uninjured brain regions. We hypothesized that plasticity of the uninjured hemisphere occurs contralateral to a focal TBI in the adult rat. Thus, we performed cortical mapping of the cortex contralateral to the TBI using intracortical microstimulation (ICMS).

Pubmed ID: 23047494

TBI Model

  • Weight-drop model
  • Weight-drop

    • Animal Information

  • Species: rat
  • Strain:
  • Age (weeks): No age reported
  • Weight (grams): No weight reported

    • Assessments

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Department of Neurosciences, School of Medicine

    University of California, San Diego





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