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A murine model of mild traumatic brain injury exhibiting cognitive and motor deficits.

SH Yang | J Gustafson | M Gangidine | D Stepien | R Schuster | TA Pritts | MD Goodman | DG Remick | AB Lentsch
The Journal of surgical research | 2013 Oct

Mild traumatic brain injury (TBI) is a serious public health concern affecting more than 1.7 million people in the United States annually. Mild TBI is difficult to diagnose and is clinically associated with impaired motor coordination and cognition.

Pubmed ID: 23622728

TBI Model

  • Weight-drop model
  • Closed head Injury

    • Animal Information

  • Species: mouse
  • Strain: C57/BL6
  • Age (weeks): 8 - 10
  • Weight (grams): No weight reported

    • Assessments

    ELISA, Histology, Magnetic Resonance Imaging, Novel object recognition, righting reflex response, rotarod

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Contact Us

    Department of Neurosciences, School of Medicine

    University of California, San Diego





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