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Microparticles impact coagulation after traumatic brain injury.

EF Midura | PL Jernigan | JW Kuethe | LA Friend | R Veile | AT Makley | CC Caldwell | MD Goodman
The Journal of surgical research | 2015 Jul

The pathophysiology that drives the subacute hypercoagulable state commonly seen after traumatic brain injury (TBI) is not well understood. Alterations caused by TBI in platelet and microparticle (MP) numbers and function have been suggested as possible causes; however, the contributions of platelets and MPs are currently unknown.

Pubmed ID: 25846728

TBI Model

  • Weight-drop model

    • Animal Information

  • Species: mouse
  • Strain: C57BL/6
  • Age (weeks): 6 - 8
  • Weight (grams): 20 - 28

    • Assessments

    Rotational thromboelastometry

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Department of Neurosciences, School of Medicine

    University of California, San Diego





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