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The protective effect of the ketogenic diet on traumatic brain injury-induced cell death in juvenile rats.

ZG Hu | HD Wang | L Qiao | W Yan | QF Tan | HX Yin
Brain injury | 2009 May

The ketogenic diet (the KD) is an effective treatment for intractable epilepsy, especially in the paediatric population, and a growing number of studies have shown the neuroprotective role of the KD. However, few studies focused on the neuroprotective effects of the KD in traumatic brain injury (TBI). The present study aimed to investigate the effects of the KD on TBI.

Pubmed ID: 19408168

TBI Model

  • Weight-drop model
  • Feeney’s Weight-drop model

    • Animal Information

  • Species: rat
  • Strain: Sprague-Dawley
  • Age (weeks): 5 - 5
  • Weight (grams): No weight reported

    • Assessments

    rt-PCR, Western blot, Brain water content, TUNEL staining, Apoptosis test

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Department of Neurosciences, School of Medicine

    University of California, San Diego





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