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Increased intestinal inflammatory response and gut barrier dysfunction in Nrf2-deficient mice after traumatic brain injury.

W Jin | H Wang | Y Ji | Q Hu | W Yan | G Chen | H Yin
Cytokine | 2008 Oct

To explore the role of nuclear factor erythroid 2-related factor 2 (Nrf2) in traumatic brain injury (TBI)-induced intestinal inflammatory response and gut barrier dysfunction in the mice.

Pubmed ID: 18722136

TBI Model

  • Weight-drop model

    • Animal Information

  • Species: mouse
  • Strain: ICR
  • Age (weeks): 6 - 8
  • Weight (grams): 28 - 32

    • Assessments

    ELISA, EMSA, Immunohistochemistry (IHC), lactulose/mannitol (L/M) test, limulus amebocyte lysate (LAL) test

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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    Contact Us

    Department of Neurosciences, School of Medicine

    University of California, San Diego





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