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Bumetanide administration attenuated traumatic brain injury through IL-1 overexpression.

KT Lu | CY Wu | HH Yen | JH Peng | CL Wang | YL Yang
Neurological research | 2007 Jun

To examine the effects of administration of bumetanide, a specific NKCC1 inhibitor, on traumatic brain injury (TBI)-induced interleukin-1 (IL-1) expression.

Pubmed ID: 17626737

TBI Model

  • Weight-drop model
  • Animal Information

  • Species: rat
  • Strain: Wistar
  • Age (weeks): No age reported
  • Weight (grams): 350 - 400
  • Assessments

    RT-PCR, Brain Water Content, Western blot, Hematoxylin and eosin

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available
  • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available