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The Effects of Shilajit on Brain Edema, Intracranial Pressure and Neurologic Outcomes following the Traumatic Brain Injury in Rat.

M Khaksari | R Mahmmodi | N Shahrokhi | M Shabani | S Joukar | M Aqapour
Iranian journal of basic medical sciences | 2013 Jul

Brain edema is one of the most serious causes of death within the first few days after trauma brain injury (TBI). In this study we have investigated the role of Shilajit on brain edema, blood-brain barrier (BBB) permeability, intracranial pressure (ICP) and neurologic outcomes following brain trauma.

Pubmed ID: 23997917

TBI Model

  • Weight-drop model
  • Marmarou's Weight-drop model
  • Animal Information

  • Species: rat
  • Strain: Albino
  • Age (weeks): No age reported
  • Weight (grams): 250 - 300
  • Assessments

    Evans blue dye, Intracranial pressure assessment, Veterinary Coma Scale, blood - brain –barrier permeability, Brain water content

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available
  • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available