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Accumulation of connective tissue growth factor+ cells during the early phase of rat traumatic brain injury.

Y Liu | Z Liu | X Li | B Luo | J Xiong | W Gan | M Jiang | Z Zhang | HJ Schluesener | Z Zhang
Diagnostic pathology | 2014 Jul 10

Glial scar formation is a common histopathological feature of traumatic brain injury (TBI). Astrogliosis and expression of transforming growth factor beta (TGF-β) are key components of scar formation and blood-brain barrier modulation. Connective tissue growth factor (CTGF) is considered a cytokine mediating the effects of TGF-β.

Pubmed ID: 25012526

TBI Model

  • Weight-drop model
  • Animal Information

  • Species: rat
  • Strain: Lewis
  • Age (weeks): 8 - 9
  • Weight (grams): 350 - 400
  • Assessments

    Immunohistochemistry

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available
  • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available