Searching across hundreds of databases

Our searching services are busy right now. Please try again later

  • Register
X
Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

X

Leaving Community

Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.

No
Yes

Lactobacillus acidophilus Exerts Neuroprotective Effects in Mice with Traumatic Brain Injury.

Y Ma | T Liu | J Fu | S Fu | C Hu | B Sun | X Fan | J Zhu
The Journal of nutrition | 2019 Sep 01

Traumatic brain injury (TBI) causes dysbiosis and intestinal barrier disruption, which further exacerbate brain damage via an inflammatory pathway. Gut microbiota remodeling by Lactobacillus acidophilus (LA) is a potential intervention.

Pubmed ID: 31174208

TBI Model

  • Weight-drop model

    • Animal Information

  • Species: mouse
  • Strain: C57BL/6
  • Age (weeks): 8 - 9
  • Weight (grams): 18 - 24

    • Assessments

    16S ribosomal RNA gene sequencing, Blood–brain barrier permeability, Enzyme-linked immunosorbent assay (ELISA), Histology, RT-PCR, Western blot, Brain water content, limulus amebocyte lysate assay, Neurological Severity Score (NSS), Rotarod test

    TBI model parameters

  • Impact Depth (mm): No information available
  • Impact Duration (ms): No information available
  • Impact Velocity (m/s): No information available
  • Impactor Tip: No information available

    • Device Name

    No information available

    Associated Datasets

    No information available

    Associated Protocols

    No information available

    About

    The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

    Recent News Entries

    Contact Us

    Department of Neurosciences, School of Medicine

    University of California, San Diego





    About SciCrunch | Privacy Policy | Terms of Service

    SciCrunch